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KMID : 0613820120220050687
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Journal of Life Science
2012 Volume.22 No. 5 p.687 ~ p.691
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Opposite Localization of Luteinizing Hormone Receptors and Galectin-3 in Mature Mouse Ovaries
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Kim Ju-Hwan
Yang Mi-Young
Kim Sung-Ho
Kim Jong-Choon
Kim Seung-Joon
Joo Hong-Gu
Shin Tae-Kyun
Moon Chang-Jong
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Abstract
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The present study evaluated the localization of luteinizing hormone receptors (LHR) and galectin-3 (Gal-3), a beta-galactoside-binding animal lectin, in the mature mouse ovaries by immunohistochemical analysis. Intense LHR immunoreactivity was detected in the active corpus luteum (CL), whereas expression of Gal-3 was high in the regressing CL and atretic follicle. In the CL of pregnant mice, LHR immunoreactivity was intense, but Gal-3 expression was low. Thus, LHR and Gal-3 had opposite patterns of expression in mature mouse ovaries, suggesting that both proteins have stage-specific expression patterns and are possibly involved in CL formation and regression.
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KEYWORD
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Luteinizing hormone receptor, galectin-3, corpus luteum, follicle, mouse ovary
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